Postdoctoral Researcher Job at Mass General Brigham, Boston, MA

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  • Mass General Brigham
  • Boston, MA

Job Description

We are recruiting a highly motivated postdoctoral researcher to join our spatial proteomics laboratory located at the Broad Institute , where we apply mass spectrometry-based spatial proteomics to human skin disease .

Position available from June 2026

Who we are

Our lab addresses fundamental questions in human skin disease, with recent publications in Nature and Nature Methods , including the discovery of a JAK inhibitor-based treatment for a lethal skin disease. We aim to bridge the gap between molecular discovery and clinical translation, and offer access to patient cohorts at MGH, our own state-of-the-art proteomics platform, and the scientific environment of the Broad Institute.

What we offer

  • A research program designed for high-impact publications at the interface of proteomics and translational medicine, for real-world clinical impact
  • Expertise in Deep Visual Proteomics (DVP)
  • A dedicated Orbitrap Astral Zoom platform and full proteomics infrastructure
  • Access to deeply phenotyped patient cohorts
  • The intellectual environment of the Broad Institute and Harvard Medical School
  • Mentorship toward an independent scientific career

What we are looking for

The ideal candidate is a hands-on mass spectrometrist with:

  • A PhD in analytical chemistry, biochemistry, proteomics, or a related field
  • Deep practical experience operating and optimizing modern mass spectrometers and LC-MS workflows (3+ years)
  • Hands-on experience with proteomics sample preparation, including low-input or FFPE tissue workflows
  • First-author publications and a genuine curiosity about biology, with a track record of technical innovation: you have built, improved, or solved something others had not
  • Comfort with data analysis scripting (Python or R)
  • The drive to push limits in a clinically meaningful direction
  • Excellent written and spoken English

How to apply

Please include a CV, a brief statement of your research interests & technical background (half page), and contact information for two referees.

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