Job Description

Principal Investigator (Board‑Certified Psychiatrist)

Orange County (CA)

Full-Time * Onsite (5 days/week)

Clinical Research Site

Company Overview

We are a nationally recognized clinical research organization with 20+ sites across the United States. Our multi‑site network conducts Phase I-IV clinical trials for leading biopharma partners, supported by dedicated clinical units, advanced safety infrastructure, and experienced research staff. Physicians here work at the forefront of innovation, contributing to therapies that improve outcomes for patients living with psychiatric and neurologic conditions, while operating in a collaborative, professionally run, and patient‑centered environment.

Position Summary

We are seeking a Board‑Certified Psychiatrist to serve as Principal Investigator (PI) at our research site in Orange County. The PI provides medical and scientific oversight for clinical trials, ensures participant safety, and upholds protocol and regulatory compliance.

Key Responsibilities

• Serve as Principal Investigator for assigned clinical trials, providing medical leadership and oversight.
• Conduct psychiatric evaluations and diagnostic assessments.
• Assess subject eligibility and compliance with investigational product and scheduled visits.
• Evaluate participant responses to therapy and manage adverse events in accordance with protocol.
• Maintain complete familiarity with all investigational product(s) used in assigned studies.
• Collaborate with the Site Director, Study Coordinator, and Recruitment Manager to support enrollment planning and execution.
• Ensure staff are trained and operating in compliance with SOPs, GCP, and protocol requirements.
• Confirm that the site maintains adequate staffing, resources, and facilities needed for successful study conduct.
• Maintain an up‑to‑date curriculum vitae and all required training and certification files.
• Promote adherence to FDA regulations, ICH‑GCP guidelines, and company SOPs.
• Document protocol deviations, unanticipated issues, and any premature unblinding events.
• Communicate promptly with IRBs, sponsors, and internal teams as required.
• Ensure accurate, complete, and audit‑ready clinical trial documentation.
• Provide oversight, guidance, and mentorship to Sub‑Investigators.
• Review Sub‑Investigator work to ensure adherence to protocols and regulatory standards.
• Foster a productive, professional, and compliant work environment for clinical staff.

Education/Experience/Skills:

• Must be able to effectively communicate verbally and in writing.
• Board Certified M.D. (Preferably in Psychiatry)
• Three years experience conducting psychiatry clinical trial research as either a PI or Sub-Investigator or have other highly relevant experience.
• Active DEA license or able to obtain one.

Compensation & Benefits

• Competitive compensation based on experience
• Medical, dental, and vision benefits
• Matching 401(k)
• Paid time off and holidays
• Opportunities for training and professional development

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